Curso. XIV Escuela Latinoamericana de Neurociencias.
Organizador(es): Instituto de Investigaciones Biológicas Clemente Estable.
Lugar: Instituto de Investigaciones Biológicas Clemente Estable.
Dirección: Avda. Italia 3318. Montevideo, Uruguay.
Fecha: 16/3/2009 3/4/2009.
Invitados especiales:
Algunos de los profesores invitados:
Washington Buño (España), Catherine Carr (USA), Pablo Castillo (USA), John Hildebrand (USA), Peter Narins (USA), Marco Tulio Núñez (Chile), Alberto Pereda (USA), Juan Segura Aguilar (Chile), Philip Stoddard (USA), Lidia Szczupak (Argentina), Daniel Tomsic (Argentina),Carol Troy (USA).
Directores:
Omar Macadar, Federico Dajas
Comité Organizador:
Michel Borde, Patricia Cassina, Silvia Olivera, José Luis Peña,
Giselle Prunell, Raúl Russo, Ana Silva, Cecilia Scorza.
Temario:
Preliminary Program:
1st module: March 16th to 21st: Cellular Neurophysiology and Synaptic Plasticity
Monday March 16th
Morning:
Opening lecture. Neuron, Synapsis and Circuits. Introduction to Electrophysiology. Electrophysiology of the neuron.
Afternoon:
Experimental seminars
Tuesday March 17th
Morning:
Development of nervous system. The establishment of neuronal polarity. Progress in cortical neurogenesis. Neuronal plasticity in adult brain circuits.
Afternoon:
Experimental seminars
Wednesday March 18th
Morning:
Patterns of cortical neurogenesis. Neurogenesis in the adult hippocampus. Does adult neurogenesis recapitulate embryogenesis?
Afternoon:
Experimental seminars
Evening:
Barro negro, teatro sobre ruedas
Round table: Animal care policies in Latin America.
Chairs: Annabel Ferreira, Cecilia Scorza, Ana Silva.
Thursday March 19th
Morning:
New tricks at old structures: novel forms of synaptic plasticity. Modulation of «spike timing dependent plasticity» (STPD). Electric synaptic transmission
Afternoon:
Experimental seminars
Friday March 20th
Morning:
Plasticity in an electric synapsis. Persistent muscarinic potentiation of the synaptic efficacy. Endocannabinoid-mediated synaptic plasticity in the CNS.
Afternoon:
Experimental seminars
Saturday March 21st
Morning
Mini-symposium: Neuron and neural circuits: neural codes and plasticity.
Degeneracy in neural circuits. The control of breathing.
Neural plasticity in spinal circuits.
Neural coding at primary sensory afferences
Filter properties of neurons and circuits.
Chairs: Angel Caputi, Nicholas Mellen.
Afternoon
Student oral presentation (part I)
2nd module: March 23rd to 30th: Neuron-glia interaction and nervous system pathology
Monday March 23rd
Morning: Neuron-glia communication
An overview of CNS neurochemical interactions.
Astrocyte biochemistry and physiology.
Afternoon:
Experimental seminars
Tuesday March 24th
Morning: Oligodendrocytes, Schwann cells and microglia
Introducing oligodendrocytes and Schwann cells. Myelination. Microglia.
Afternoon:
Presentation of experimental seminars by students
Wednesday March 25th
Morning: Role of glial cells in pathology
Rol of astrocytes determining neuron survival. Demyelination. Role of microglia in neuroinflammation.
Afternoon:
Experimental seminars
Thursday March 26th
Morning: How to assess glial cell partipation in pathology?
In vitro and in vivo approaches. Recent molecular approaches to identify underlying pathomechanisms. How to study demyelinating pathologies: a clinical view. PET to assess glial reactivity in neurodegeneration.
Afternoon:
Experimental seminars
Evening:
Mini-Symposium: Neurodegeneration and Neuroprotection
Chairs: Patricia Cassina, Silvia Olivera, Giselle Prunell.
Friday March 27th
Morning: Mechanisms underlying neurodegeneration
Neurodegenerative diseases: propossed pathological mechanisms. Different pathways leading to neuronal death. Oxidative stress and neurodegeneration.
Afternoon:
Experimental seminars
Saturday March 28th
Morning: Parkinson disease as a prototypic neurodegenerative disease
Introducing to Parkinson disease. Iron participation in Parkinson disease. Nicotinic receptor protection against Parkinson disease.
Afternoon:
Student oral presentation (part II)
Monday March 30th
Morning: State of the art of neuroprotective approaches
Cre/lox technology
siRNA delivery to neurons
Gene therapy against neurodegeneration
3rd module: March 30th to April 3rd: Systems underlying behaviour: Neuroethology
Monday March 30th
Evening:
Round table: How to develop a scientific career.
Chairs: John Hildebrand, Omar Macadar.
Tuesday March 31st
Morning:
Principles of Neural Systems. Neural networks and neural codes. Parallel evolution of neural processing patterns.
Afternoon:
Experimental seminars
Wednesday April 1st
Morning:
Sensory processing and behaviour. Sound localization. Chemoreception. Vision in invertebrates.
Afternoon:
Experimental seminars
Thursday April 2nd
Morning:
Neural bases of motor strategies. Locomotor behaviour. Electromotor systems. Communication calls.
Afternoon:
Presentation of experimental seminars by students.
Evening:
Symposium on neural bases of behavior
Chairs: Catherine Carr, Peter Narins.
Friday April 3rd
Morning:
Behavioral plasticity. Long term visual memory in arthropods. Circadian variations of an electromotor output. Sexual and seasonal plasticity of the CNS.
Afternoon:
Meeting of the IBRO-LARC Council
Closing lecture. Closing ceremony. Party.
Experimental seminars
Module 1:
– Physiology of an inhibitory synapsis in vitro
Inés Pose, Sebastián Curti. Fac. de Medicina, UdelaR
– Electric properties of neurons in the CNS.
Raúl Russo – Cecilia Reali. IIBCE.
– In vivo análisis of excitatory and inhibitory synapsis in the CNS of vertebrates.
Michel Borde – Alberto Pereda. Fac. de Medicina. UdelaR
– Synaptic plasticity in vitro.
Pablo Castillo. IIBCE.
– Neuronal designs for the elaboration of rhythmic efferences in the CNS.
Nicholas Mellen, Jean-René Cazalets. Fac. de Medicina, UdelaR
– Astrocyte-mediated neurotoxicity to motorneurons.
Patricia Cassina y Hugo Peluffo. Facultad de Medicina, UdelaR
– Astrocyte response to injury and its effects on CNS neurons survival.
Silvia Olivera y Giselle Prunell, IIBCE
Module 2:
– Myelination in in vitro models.
Alejandra Kun y José Sotelo, IIBCE
– Evaluation of brain performance by in vivo microdyalisis and behavior.
Cecilia Scorza y Juan Andrés Abin, IIBCE
– Hypoxic-ischemic models and evaluation of brain damage.
Fernanda Blasina y Felicia Rivera, IIBCE
– Neural bases of visual and auditory perception.
José Luis Peña, Leonel Gómez. Facultad de Ciencias, UdelaR.
– Neural mechanisms of the novelty response.
Angel Caputi, IIBCE.
– Modulation of reproduction and aggression.
Ana Silva, Philip Stoddard, Kent Dunlap, IIBCE.
-Neural bases of maternal behavior
Annabel Ferreira, Facultad de Ciencias, UdelaR
-Role of the Pontine Reticular Formation in the generation of REM sleep.
Pablo Torterolo, Patricia Lagos. Facultad de Medicina, UdelaR.
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